Adjust oven rack to middle position and heat oven to 475 degrees. Spray 13-by-9-inch baking dish with vegetable spray.

In large bowl, use rubber spatula to combine panko and milk. Let mixture sit for 5 minutes.

Meanwhile, use your hands to break pasta in half over greased baking dish. Spread pasta into even layer. Pour marinara sauce and water over pasta and use tongs to toss gently until coated.

Add beef, Parmesan, garlic powder, oregano, and salt to bowl with panko mixture and use your hands to gently mix until evenly combined.

Roll beef mixture into 15 meatballs (about 2 tablespoons each). Place meatballs in baking dish on top of pasta. Wash your hands.

Cover baking dish tightly with aluminum foil. Place baking dish in oven and bake for 30 minutes.

Use oven mitts to remove baking dish from oven and place on cooling rack (ask an adult for help). Carefully remove foil and discard. Use tongs to stir pasta thoroughly, scraping sides and bottom of dish (be careful – baking dish and sauce will be HOT!).

Return baking dish to oven and continue to bake, uncovered, until pasta is tender and sauce is thickened, 5 to 8 minutes.

Ask an adult to remove baking dish from oven and place on cooling rack. Let pasta cool for 10 minutes.

Use tongs to carefully toss to coat pasta and meatballs with sauce. (If sauce is too thick, add extra hot water, 1 tablespoon at a time, until loosened.). Sprinkle with basil and serve with extra Parmesan.